Overview of Seminole Casino Hotel You will find Seminole Casino Hotel at 506 South 1st Street in Immokalee, Florida. They feature over 1,400 slot machines here, plus live table gaming action featuring some of your favorite Vegas-style pgslot games. Seminole Casino Hotel also offers immense promotions which grow even sweeter when you become a member of the Seminole Wild Card Rewards Program. Not only will you maximize all the casino promos, you will also have the opportunity to win rewards points that you can exchange for an array of benefits.